no... not that i remember... since my first pc in 98.
in my opinion you really have to be (if not a novice) an idiot to get a virus. i don't get all the security/insecurity buzz.
in fact, i just install an antivirus from time to time to see how things are going, and get the same false positives of always about some keygens (oops! never said that!). no more security measures and i'm no genius (well, maybe that is false modesty).
just download everything from official sites, or renowned sites. in my case betanews, softpedia, or filehippo. and that's the magic formula. security BS panic over the web is just business.