Probably not, depending on your drivers and BIOS rev. I haven't heard anything bad about using that combo. The guys at <A HREF="http://www.nforcershq.com/forum" target="_new">nForcersHQ</A> know everything about nForce2 and compatibility, you can double check with them.
<A HREF="http://www.anandtech.com/mysystemrig.html?id=24106" target="_new">My System Rig</A>
<A HREF="http://service.futuremark.com/compare?2k3=535386" target="_new">3DMark03</A>