Firstly there is no need to wish such an outcome on anyone, or mention the 'Big C' in such a way. Please refrain from that, and edit your post. It's inappropriate.
Regarding the steam install, it's worth doing a file check (verify integrity of game files) and re-installing if you haven't already. I've the same set up (R6 through Steam, connected to Uplay) and the same happened to me, but is working flawlessly now.