ROTTR can be extremely demanding, especially in the Soviet Installation and Geothermal sections, it's also very hard on the CPU.
Suggestions:
Update all your drivers.
Update the game to it's latest patch.
Try switching to DX 12.
Try here: http://www.dsogaming.com/news/rise-of-the-tomb-raider-sli-fix-found-offering-95-sli-scaling-on-two-nvidia-gpus/
Either lower the settings or move to a single display, my setup (i7 6500+R9 Nano) hits a wall in the super demanding sections on a single 1080 monitor with FPS dropping to well under 60 FPS in Soviet Installation and Geothermal sections.