Dual channel memory is one of those technologies which shows an impressive 20%-40% speedup in memory benchmarks. But in real-world benchmarks it only translates into a 0%-5% speedup. There just aren't that many situations when your computer's performance is limited by memory bandwidth.* A few years back I accidentally put the memory sticks in the wrong slots on my gaming system. I ended up running in single channel mode for 2 years before I noticed the error. I put the sticks in the correct slots, started the computer up and... saw no perceivable difference in performance.
Since you can get dual channel for free when building your computer, go ahead and use it (buy your memory sticks in pairs - the dual channel slots are...