Yes, if your motherboard or RAID controller supports RAID 10. I seem to recall that you need to configure the drives as RAID first, then install the RAID drivers during the installation of Windows (assuming Windows is your OS).
Why wouldn't it be? If you have the space and connections, no problem...assuming you have a hardware RAID controller or your motherboard supports the configuration.
Yes, if your motherboard or RAID controller supports RAID 10. I seem to recall that you need to configure the drives as RAID first, then install the RAID drivers during the installation of Windows (assuming Windows is your OS).