P00P34 :
USAFRet :
Yes. Install the OS on the SSD with only the SSD connected.
After it is all working, reconnect the HDD.
Preferably, you then completely wipe the HDD completely.
Then use it as needed.
It will be just another drive letter.
Is there a better reason to wipe the drive rather than just leaving it?
Wasted space, and potential troubleshooting confusion later. Yes, I've seen that confusion: "Oops...I still had the old OS on the other drive, and that is what I was looking at"...stuff like that.
Also, you have to be very careful on your future installation locations, and BIOS boot order.
You applications will have to be reinstalled anyway (new OS). Steam/Origin games can be moved elsewhere during the wipe, and then moved back as needed.
Much better to start with a completely clean drive.