Question System IO shuts off randomly

Feb 19, 2019
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I've just upgraded my PC and now I'm occasionally getting an issue where the computer just completely becomes unresponsive. The video turns off (monitor says no signal), mouse lights turn off, keyboard caps lock doesn't respond, etc. This happens randomly, but more often than not when I'm using a lot of CPU power, like rendering in blender. I tried resetting CMOS, no difference. Any thoughts?

Specs:
AMD Ryzen 5 2600
Zotac 1080ti Amp Core Extreme
ASUS x470 PRO
WD Blue 500GB SSD
Seasonic Focus+ Gold 650W PSU