Not seen that before. I doubt loading in safe mode would prove anything, its likely a program causing it and not a driver.
Try a clean boot and see if it fixes it - read instructions carefully and make sure not to disable any Microsoft services or win 10 may not load right -
https://support.microsoft.com/en-au/help/929135/how-to-perform-a-clean-boot-in-windows
what do the arrows in white area do? have you unlocked the taskbar and seen if you can drag it to right? right click taskbar and see if anything strange showing in the toolbar menu
if that helps, its likely caused by a startup program, slowly (Over a few startups) re enable them one at a time until you find cause. Then we try to figure out why, it might be a setting in one of...