Your rendering would benefit more by having the K80 in the X16 slot. I assume rendering is why you are asking about a K80.Can i use NVIDIA Tesla K80 with x8 to x16 PCI adapter ?, i use supermicro motherboards, they only have 1 PCI-E 3.0 x16, 6 PCI-E 3.0 x8 slots, and used x16 PCI-E for GPU
Yes, i use x16 cards for RX 5500 XT, or can i use RX 5500 XT with x8 to x16 adapter ?, i use triple monitor setupYour rendering would benefit more by having the K80 in the X16 slot. I assume rendering is why you are asking about a K80.