Justins87gnx :
SLI/Crossfire does not run well at all in DX12 resulting less FPS if you have SLI enabled, it’d only work for DX11 and past that.
However if you truly need it for something other than gaming, then by all means go for it, however in a gaming situation a single 1080 Ti would do MUCH better than dual 580’s even.
Well technically there is no Crossfire or SLI (driver based) support for the DX12 API. Crossfire/SLI is for DX11 or earlier.
Multiple GPUs can only be used in DX12 games/applications if the developer has specifically programmed support into the code. So the emphasis is no longer on AMD or Nvidia to optimise their drivers or create a profile for a game to support Crossfire/SLI.
What was initially heralded as a positive step forward for multi GPU implementation (giving full control to devs) has so far resulted in just a small handful of DX12 games featuring any support at all. It seems to work well when it is adopted though.
http://www.tomshardware.co.uk/answers/id-3142821/dx12-vulkan-games-supporting-multi-gpu.html
https://en.wikipedia.org/wiki/List_of_games_with_DirectX_12_support
As for the present state of Crossfire/SLI in DX11 etc., it seems that many newer games either don't support it or it's buggy. Even the likes of Battlefield 1, using Frostbite 3 now have issues. Previously the likes of BF3 and BF4 (using the same/similar engines) have enjoyed good support.
I often used to 'force' Crossfire or create/use an existing custom profile, but I'm having less and less success with that recently. Where you see even less support is when you add a third card. It either doesn't work at all or there is little scaling or visual bugs/glitches.
http://amdcrossfire.wikia.com/wiki/Crossfire_Game_Compatibility_List
https://www.geforce.com/games-applications/technology/sli?title=&sort_bef_combine=created%20DESC&sort_order=DESC&sort_by=created
https://hardforum.com/threads/name-games-that-dont-work-with-multi-gpu.1930283/
Note that these lists are not exhaustive. Games such as Rocket League work well with Crossfire, yet don't appear in many lists.