Question USB ports 'refresh' on their own

Mar 25, 2019
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I built a PC for my wife to use at work. There seems to be a 'hiccup' of sorts every couple hours where the USB devices are disconnected and reconnect. The first set of wireless Logitech keyboard/mouse wasn't compatible with usb 3.0, but still having problem with other USB peripherals.
This is my first win10 build and first mini ITX. Everything else with the computer seems flawless, hoping there is a simple fix.

Asus Rog Strix b450i
16gb ddr 3000mhz
500gb m.2
ryzen 5 2600
gtx 1060 geforce
600w PSU
 

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