We recommend using DVI since VGA does not work very well at higher resolution.
It starts to get blurry at 1920*1080.
DVI does not have this issue.
Image output from DVI is more crystal clear and looks more digital in my opinion.
You have to test both at the same time to see the difference.
Considering you are using an APU, VGA is the least of your problems. The only issue you'll have is not being able to play digitally protected DVDs/Blu rays. But your APU will give out before you'll need to worry about using VGA.