I fixed the problem and this is no longer an issue. I am unable to delete this post. If a moderator read this please feel free to delete this.
The problem was caused by 4 trojans. I use Malwarebytes, (the paid version that runs all the time), and Avast. I had Malwarebytes scheduled to scan once a day, and Avast scanned once a week. Neither picked the trojans up. I uninstalled both and activated Windows Defender and ran a scan. Defender caught those so that is all I am going to use from now on. I purchased the iBoySoft Data Recovery tool to recover all my files on the E drive. That tool is extremely fast and very easy to use. It is well worth the money in my opinion.
Part of the error message I was getting about "making sure the system drivers are loaded" got me thinking. I checked my system and found that something changed my boot up from Normal to Safe boot where only the necessary system drivers would load. I've never had a problem with my system so I know I didn't change it. It must have been one of the Trojans. I then ran the DISM commands and SCF. It found and fixed the corrupted system files.
The end result is I am back up and running better than ever.
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The E: Drive shows up in File Explorer but when I click on it I get:
You need to format the disk in drive E: before you can use it.
The volume does not contain a recognized file system. Please make sure all required file system drivers are loaded and the volume is not corrupted.
Disk Management shows E: as Online, 931.51 GB RAW Healthy (Primary Partition). Event Viewer shows no disk errors or events for any disks.
I feel certain that the data is there, and am hoping that maybe the FAT table or something just got corrupted and can easily be repaired. Is there such an animal?
)
The E: drive is my Data/App drive so I need everything on it. I am running a program called TestDisk to attempt to recover the files so I can reformat the drive, but that will be my last resort.
I did have serious issues with the C: and F: drive which I explain below.
BACKGROUND INFO:
After updating the firmware on the C: (OS) drive, I continued to use the system with no problems until I shut the system down and booted the next day. I got the "Operating system failed to load" message.
So I booted from the Win 10 repair disk and tried all the options. The System Image Recovery option found 1 file to use located on my F: drive which is an external 1TB USB drive used for backups. After I began the process I reread the screen and it looked like it was going to restore to the F: drive instead of the C: drive so I immediately stopped it.
I tried to look at the F: drive and was unable to access it. So I plugged it into my old Win XP system and it couldn't see the drive either
) Then I plugged it back into the Win 10 and I was able to access it with no problem.
I finally ran the bootrec /FixMbr, bootrec /FixBoot, bootrec /ScanOs, and bootrec /RebuildBcd commands on the C: drive and that fixed the failure to boot problem.
The problem was caused by 4 trojans. I use Malwarebytes, (the paid version that runs all the time), and Avast. I had Malwarebytes scheduled to scan once a day, and Avast scanned once a week. Neither picked the trojans up. I uninstalled both and activated Windows Defender and ran a scan. Defender caught those so that is all I am going to use from now on. I purchased the iBoySoft Data Recovery tool to recover all my files on the E drive. That tool is extremely fast and very easy to use. It is well worth the money in my opinion.
Part of the error message I was getting about "making sure the system drivers are loaded" got me thinking. I checked my system and found that something changed my boot up from Normal to Safe boot where only the necessary system drivers would load. I've never had a problem with my system so I know I didn't change it. It must have been one of the Trojans. I then ran the DISM commands and SCF. It found and fixed the corrupted system files.
The end result is I am back up and running better than ever.
_______________________________________________________________
The E: Drive shows up in File Explorer but when I click on it I get:
You need to format the disk in drive E: before you can use it.
The volume does not contain a recognized file system. Please make sure all required file system drivers are loaded and the volume is not corrupted.
Disk Management shows E: as Online, 931.51 GB RAW Healthy (Primary Partition). Event Viewer shows no disk errors or events for any disks.
I feel certain that the data is there, and am hoping that maybe the FAT table or something just got corrupted and can easily be repaired. Is there such an animal?

The E: drive is my Data/App drive so I need everything on it. I am running a program called TestDisk to attempt to recover the files so I can reformat the drive, but that will be my last resort.
I did have serious issues with the C: and F: drive which I explain below.
BACKGROUND INFO:
After updating the firmware on the C: (OS) drive, I continued to use the system with no problems until I shut the system down and booted the next day. I got the "Operating system failed to load" message.
So I booted from the Win 10 repair disk and tried all the options. The System Image Recovery option found 1 file to use located on my F: drive which is an external 1TB USB drive used for backups. After I began the process I reread the screen and it looked like it was going to restore to the F: drive instead of the C: drive so I immediately stopped it.
I tried to look at the F: drive and was unable to access it. So I plugged it into my old Win XP system and it couldn't see the drive either

I finally ran the bootrec /FixMbr, bootrec /FixBoot, bootrec /ScanOs, and bootrec /RebuildBcd commands on the C: drive and that fixed the failure to boot problem.