Weird Box appearing on my screen

[ExicionZ]

So i have been playing games and lately some boxes appear on my screen and just flicker. They look like black pixles or white and idk what they mean. They really annoy me and i havent been able to find a fix. I tried updating graphics. I tried lowering clocks. Im not sure what to do anymore.
https://gyazo.com/32662f17a309229aff52285f8818a3e1

 

[renz496]

That big white box? Have you tried doing clean driver install uaing DDU? What is your syatem spec?