All of these are great ideas, but not really what I am looking for. It sounds like it is going to be a bit harder than I though to get an MATX option. MITX isn't really an option for me, as I need the high ram capacities and full x-series chip-set support. I am even considering the EVGA hadron at this point, as you can fit an matx mobo in there with a little bit of modding.
As for storage, I literally could care less. All of my storage is going to be m.2, so no need for HDD or SSD support. I was a little interested in the Cerberus case (project MATX, formerly Nova) that I have been following for quite some time. The real need here for me is SFF with a serious punch. I have triple monitors, and not much space left on my desk, and I also like to bring my PC around to places (road trips, flights, etc.). And NO, a laptop will NEVER do. I am using a 16-core xeon in this monster, so there is that.
As for the case you suggested, crossfire, it only has half-height PCI slots. High-power DGPUs are right out of the question with those.
On a separate note, I can easily build my own case. I have been modding for a few years now, and now I am finally at the point of building my own. I am extremely active on overclock.net's scratch build thread and things alike.