There's no point, just because the case is bigger it doesn't mean that there will be any benefit in terms of airflow, or if it is even needed.
My above build gives you plenty of cooling, and a separate HDD and SSSD.
An SSD will give next to no benefit to stuff apart from OS and software, and will give a significantly faster dedicated speed compared to a hybrid drive, hence why SSHDs aren't recommended.
The build i have mentioned has everything optimized at the cheapest you can get. The SSD is more or less essential these days for faster load times and overall functioning of your pc. And the processors mentioned in these builds are locked and comes with stock coolers which are plenty to keep them cool.