Sorry bro, not even quad Maxwell Titan Xs can handle that, they can run 1440p though, dual Pascal Titan Xs can run any AAA game at maximum settings at 4k 60+fps with dual monitors at most. A single Nvidia 1080 can run AAA games at 60+fps on maximum settings on a single monitor. For If you want the best of the best I recomend these specs, if you have the money, of course.
CPU/Intel I7-4790k w/Frostbyte 360
GPU/Dual Titan X(Pascal)
Motherboard/Asus X99 Maximus VII Hero
PSU/Novatech 1000W Power Station V2 Black Edition
RAM/Corsair Vengeance 4GB*4
Storage/Samsung 850 Series 2 TB SSD
Case/NZXT S340 White Mid-Tower
For even better results, you might want to consider overclocking, with a liquid cooling unit on your CPU, and good enough fans on yor case, you can get you I7-4790k to run to up to 5.0 Ghz, maybe even 5.2 if you use a mineral oil case.