What happens if I remove everything from temporary files?

[MiloshDr]

On Windows 10 there is one sketchy checkbox in temporary files called "downloads folder" with the description "This folder contains files downloaded from the internet". This is whats taking up all the space on my hard drive (Taking up 131GB).

Its not letting me see what it contains, should it be safe to remove that?

 

[CountMike]

Run Disk Cleanup first, it should get rid of all unnecessary files. It's safest way. Ccleaner and UnCleaner programs can also safely remove even more.