I have watched a bunch of youtube videos showing application methods and quite a few of them show no temp difference or not big enough to make a difference. I will be mounting a Thermaltake Water 3.0 Ultimate 360mm AIO to a Ryzen 5900X. It looks like the 5 dot method is a good choice for this setup. I used Thermal Grizzly Kryonaut in my current build. Thinking of going with this again with 5 small dots.