Stevan :
Sorry, because I didn't reply but my comp. had some problems. My AGP died. There isn't any specific reason for me to ask about this file. Simply I wanted to know what is it for. Thanks for the effort, and sorry you waited my response all this time!!!
Best wishes!!!
i know its been long time this post but here is info on the npfs.sys.
Applications or services that rely on the Named Pipe File System (Npfs.sys) may encounter latency or time-out issues when many connections are made to a named pipe in Windows Server 2008 or in Windows Vista Service Pack 1 (SP1).
For example, you may find that print jobs are handled slowly or that the jobs time out and fail on a Windows Server 2008-based print server.
CAUSE
This problem occurs when too many connections are made to a named pipe. When this occurs, the Named Pipe File System takes a long time to find clients that are in the listening state.
RESOLUTION
To resolve this problem, install the following hotfix. After you install this hotfix, the NPFS maintains a new list that contains only the clients in the listening state. This new list can resolve this latency issue.
Hotfix information
A supported hotfix is available from Microsoft. However, this hotfix is intended to correct only the problem that is described in this article. Apply this hotfix only to systems that are experiencing this specific problem. This hotfix might receive additional testing. Therefore, if you are not severely affected by this problem, we recommend that you wait for the next software update that contains this hotfix.
If the hotfix is available for download, there is a "Hotfix download available" section at the top of this Knowledge Base article. If this section does not appear, contact Microsoft Customer Service and Support to obtain the hotfix.
Note If additional issues occur or if any troubleshooting is required, you might have to create a separate service request. The usual support costs will apply to additional support questions and issues that do not qualify for this specific hotfix. For a complete list of Microsoft Customer Service and Support telephone numbers or to create a separate service request, visit the following Microsoft Web site:
http://support.microsoft.com/contactus/?ws=support
Note The "Hotfix download available" form displays the languages for which the hotfix is available. If you do not see your language, it is because a hotfix is not available for that language.
Important Windows Vista and Windows Server 2008 hotfixes are included in the same packages. However, only one of these products may be listed on the “Hotfix Request” page. To request the hotfix package that applies to both Windows Vista and Windows Server 2008, just select the product that is listed on the page.
Prerequisites
To apply this hotfix on Windows Vista-based computer, you must have Windows Vista SP1 installed.
For more information, click the following article number to view the article in the Microsoft Knowledge Base:
935791 How to obtain the latest Windows Vista service pack
No prerequisites are required for Windows Server 2008-based computers.
Restart requirement
You must restart the computer after you apply this hotfix.
Hotfix replacement information
This hotfix does not replace any other hotfixes.
File information
The English version of this hotfix has the file attributes (or later file attributes) that are listed in the following table. The dates and times for these files are listed in Coordinated Universal Time (UTC). When you view the file information, it is converted to local time. To find the difference between UTC and local time, use the Time Zone tab in the Date and Time item in Control Panel.
Windows Vista and Windows Server 2008 file information notes
The MANIFEST files (.manifest) and MUM files (.mum) that are installed for each environment are listed separately . MUM and MANIFEST files, and the associated security catalog (.cat) files, are critical to maintaining the state of the updated component. The security catalog files (attributes not listed) are signed with a Microsoft digital signature.