9.999/10 your laptop won't run DDR3-1600 SO-DIMM RAM; only a very few offer BIOS setting to increase the DRAM Frequency (this is an OEM limitation). I doubt you'll see any real improvement if you already have 4GB, and instead Hibernation on/off will take a really longtime to write/read 16GB from the HDD.
Also, you need to verify that the RAM is compatible with your Notebook/Laptop; go to either your OEM or Crucial -> http://www.crucial.com/ and verify maximum capacity.