When headphones unplugged + replugged videos don't play.

[Malefic Grindylow]

So I've been having a strange problem recently which I can't find a fix for (without restarting). I've been using my DT990's outside of my pc recently so obviously I need to remove them from my amp (e10k) but whenever I come back to my PC videos on any browser or player won't load at all, I'm pretty sure there's no sound in general too but haven't tested this yet. I've tried reinstalling drivers for the e10k but to no avail.
Any ideas? I'm baffled

 

[EvilHamster]

Does this persist when you restart (not just refresh) the browser?
Does this happen for all browsers?
Does this happen to all sorts of videos? (i.e. just flash type or also other video formats)