Which is better?

The 7750 of course as a card. But remember if you have a APU, the CPU is built into it and will cause games (assuming that is the reason for the discussion) not to work, as the CPU will bottleneck. Remember data stored (HDD) is read (RAM) in chunks at a time to be processed (CPU) to decide what device (NIC, GPU, Printer) needs to perform the data code. You have the CPU / RAM / HDD in all things affect performance BEFORE the GPU gets involved. Current (2013) games demand no less then a i5/AMD 8xxx CPU with the Video card. If you have a APU system you need a new system.