I think the facts are there. Breeding our own weakens them, doesnt allow for a more natural blending of genes, and could introduce disease as well.
The use of pesticides, is well known, something made to kill will kill. Weve lost millions of people since weve banned DDT to malaria, it was that important, tho thats in Africa where no one seems to care enough, but when it comes to money, its ok to use lessor pesticides, if it only kills animals.
We need better answers here, and better knowledge to make sure what it is, if its our handling, or our pesticides, find out which one, or is its both. Then change what were doing, or how were doing it