1. We're assuming the drive in the screenshot is the 1 TB drive in question. I only raise this point since you've indicated your system contains five (5) drives and we want to be assured this is the "problem" drive. Capiche?
2. So we'll assume it is. Obviously DM indicates a "normal" secondary drive, that also contains the System Reserved partition. I assume one of your other drives is the boot drive. I'm guessing that the boot drive does NOT contain the SR partition so that you need this 1 TB drive installed upon bootup in order for the system to boot to the OS (which I guess is Win 10). So provide some info re the preceding, OK? (I'm guessing you probably previously cloned the contents of the 1 TB drive that contained the OS to the present boot drive - probably a SSD and possibly the SR partition was retained on the source (1 TB) drive - note the "Active" designation. You might also want to comment on that observation.)
3. In any event, assuming the 1 TB drive containing the F: partition is your "problem" drive, what happens if you explore its contents using DM? No data reflected?