Just like any other aio, the only differences are the mounting brackets. Up till now amd has been an all in one bracket that fit everything for the last 15yrs or so. Intel has had a couple of changes, but the brackets are designed to be adaptable for anything past lga 1155/56. For older 1366/771/775, you'd need a different bracket. It's just that the Am4 is new. And as far is I know it's slightly different. Manufacturers have already started boxing up adapters, but for those coolers made before am4 came out, you'd need to go get one from the manufacturer of your cooler. Asetek has them, it's a fact, but even ppl buying coolers now (where web pages state they have am4 brackets) are still getting older stock, so have to contact the...