Yes. Your system exceeds the recommend specs for the game. I would bet a mix of medium and high settings.
http://www.tomshardware.com/reviews/radeon-r9-290x-hawaii-review,3650-8.html
RECOMMENDED
OS Windows Vista SP2
Windows 7 SP
PROCESSOR Intel Core i5-2300
AMD Phenom II X4 940
GRAPHICS Nvidia GeForce GTX 560
AMD Radeon HD 7750
GPU MEMORY 1 GB
DirectX® 11
RAM 4 GB
HARD DRIVE 25 GB free space