I will never be 100% on the cloud, I don't care what software makers think the future holds. If I can't access it on my local machine I just don't want it. It's bad enough so many computer games come with crap like GFWL and SecuROM (at least Steam lets you play offline), but imagine if your whole computer were somehow dependant on the internet. I don't know where most of these people live, but my internet goes down, frequently (Mediacom wants me to take time off to fix THEIR problem, what a racket).
I'm not sure what the point of cloud-based profiles is. So you can log into your account on a friend's Windows 8 machine? How is that going to work, are all your apps going to be on the cloud too? I really don't care if I can access my "My Documents" folder online, if my friend doesn't have the right programs installed it won't do me any good (yes, I know Microsoft is moving Office to the cloud, but think more broadly, think non-Microsoft).