I haven't tried it alone on the hub, but I did try with only it, a keyboard, and a mouse connected to the hub. I'll try it alone tonight or tomorrow. I didn't suspect the enclosure, since it works fine plugged directly into the USB-3 adapter card, and (slower) plugged into a USB-2 port on the laptop. I have an old USB-2 hub--I think I'll try that, too, when I get a chance.
BTW, I've seen this a few times before, with other drives on a hub. Each time, I checked the drive by connecting directly to the laptop--drive showed up, opened up. I shut down, then hooked the drive back into the hub. Restart; everything fine. Not his time, though. It's that kind of behavior that makes me think it's Windows confused about what's where, rather than a hardware problem. Maybe I'll see if Linux can see it.