Fortunately, VP12 is MUCH MUCH closer to an actual (non-biased) representation of real-world application performance than was VP11. Yes, it's still "synthetic" but it uses actual code traces from updated versions of real applications -and its results are typically in-line with actual application testing results.
Unfortunately, testing in the real applications (using something like APCapc) requires actual licenses of the software apps. Many of these vendors (CATIA, NX, etc) simply don't make temp licenses available for reviewers/journalists or other non-users.
VP12 should be quite good enough to help make informed evaluations of GPU hardware. If you are concerned about seeing in-application performance measurements for particular apps, you can ususually find the data with a bit of googling, although take results you find posted on the internet by "regular Joe's" with a grain of salt.