Yes and No. You cannot run them in Nvidia SLI (multiple GPUs) as they need to be identical chips. Example: GTX 1080 + GTX 1080 = Yes, GTX 1080 + GTX 1050 = No. Besides the GTX 1050 doesn't support SLI to start with.
However you can go into the Nvidia control panel and setup the GTX 1050 as a dedicated PhysX card, it should handle this alright but i doubt you'll see a whole lot of performance improvements except the various games that use high amounts of PhysX that would benefit from it. As far as i know Arkham knight, Borderlands and Witcher 3 are good examples of PhysX games. But overall i suggest just selling it or using in a new build since you wouldn't gain much from it and it would be using up space and power that isn't...