There shouldn't be. The manufacturer of the game, Bungie, surely encorperated the games so that the usage of System Links and Wireless connectivity can both be used. As long as there is an option in the multiplayer mode, on either copy (the disc or the digital), to use a System Link, than, it should work flawlessly.
If you do encounter any issues, please feel free to message me. I am always here to help.
Thanks
Bradley