I just build in one of those cute little cases, I had some difficulty getting h100i to fit. it should make it, but the tubes are going to have to bend a bit, My friend put the motherboard in first and then tried to get the block on ( so have the back support for the cooler on the back of the motherboard) this is because trying to move a whole motherboard around with that thing squeezed in there is going to be hard. If you do that though just remember getting the block on correctly is going to be hard. the standard cooler on motherboard and them mount in case ended up working the best in my mind, but it took two sets of hands to get the radiator in.