Zotac products are awesome, but unfortunately when you put really expensive, high quality parts that make alot of heat into really small cases with 1-2 fans in them that don't dissipate heat well, you find that you leave alot of room for problems.
Zotac had come a long way in a short time. They have the best line-up of ITX boards of any manufacturer. My socket 775/Nvidia GPU board has been running great. I think it is about 2 years now since I put it together in an older ITX case. It handles anything I throw at it, except 3D, since I currently don't have the display for anyway. In a way, I wish it didn't work so well, because then I could justify getting one of these new boards.