The ASRock G41C-GS Motherboard has a PCI-E x16 2.0 slot and GTX 750 & 750Ti, has a PCI-E 3.0 interface. As PCI-E 3.0 is backwards compatible with PCI-E 2.0, you can install any PCI-E 3.0 card in your PC. It will work great. Before upgrading, make sure you have sufficient power supply wattage...