Nope, only Kaveri APUs can because in order to crossfire r7 250, because you need both graphics chips to be the same architecture. That would be GCN.
That r7 250 would also have to be DDR3 I believe if you ever upgraded to kaveri to do crossfire.
But that is a bad option, getting a really good GPU like a r7 260X even will be a lot better than APU + r7 250.