It will depend not only your chances of getting a core that can handle the increased voltage and heat but also the quality of the VRM. If you haven't purchased the card yet, I would highly suggest that you choose the Asus non-reference version. The components that they use to make the VRM is top of the line and designed for extreme OCs like you are planning. Also, their factory overclocked versions use cores that have been set aside by both AMD and Asus because of their ability to handle higher than stock clock speeds while still running at or close to the stock specs for temps and voltage. Your ability to achieve your OC goals will depend on whether or not you chose a high quality card with not only a top binned core but also a high...