Thanks guys. I have no desire in mITX, so that one is out for me. Are the mATX cases harder to build in because they're smaller, or are they still roomy enough that it's not an issue?
...
To me the selling point of an mATX case is it's compactness so that's going to dictate a certain amount additional hassle during assembly. But even so, it depends on the case since you can get some that are little smaller than a full-size ATX. Then again, there are some that are little larger than an mITX, require SFF PSU's and hardware mods to make a full complement of drives and fans fit quietly.
In my case, I've an older CM N200 and I have to angle the motherboard somewhat carefully to slip the front underneath the optical drive bay and I think it's pretty roomy for mATX. That also makes attaching some of the fan connectors a bit troublesome because the header is underneath the optical drive. Even though I may use a pair of forceps when my hand obscures what I'm trying to do I can still get to everything. I don't really consider that too much of a hassle at all.
I use an AIO for cooling so can't be certain, but I think the common practice of pre-attaching a big air cooler to the motherboard wouldn't work because of the angling it needs when installing. But most of the popular big air coolers use mounting brackets that make it easy enough to put in with the motherboard pre-installed so that shouldn't be an issue.
My case holds a 240mm AIO radiator in front and 2 120MM exhaust fans in the rear and top-rear. So ventilation is quite good enough for my 3700x processor and 5700xt GPU. For neat cable and wire management it's just as important to pre-plan the install (and where you'll route the wires) with a full size ATX. But it's important to keep in mind that a smaller case makes cable dressing even more important so as not to block airflow.
If picking one of the smaller mATX cases it's fairly easy to get one that will limit your GPU choices, usually in length. So that's something to watch for.
Otherwise, in any mATX case I've worked with I did not have to do any sort of mods to the hardware to make it fit. I did have to pay attention to maximum dimensions (like too tall of a CPU heatsink or too long of a GPU) but that was it. But even for my el-cheapo Rosewill case I was able to find standard, quality, items that worked well without too much searching.