Booting via usb

[Connorkav1]

So I have an operating system on a 3.5" internal drive. If I take it out and put it in an external 3.5" drive enclosure will it still boot but via usb(all on same computer). The OS is Windows 10 btw. The motherboard is an Asus-Z97 AR.

 

[RealBeast]

Yes it should, and HERE is a short tutorial.