Shouldn't be a problem.
What will more likely cause performance issues is trying to run too many mods. So if you attempt to run any mods at all, make sure you check for feedback on how well optimized they are and only pick a few that are.
[EDITED]
Just realized you specified record vs just play. If that is possible you'd want to do it with ReLive, as it accesses H264 encoding hardware in the chip vs recording via software, which is much less taxing on it.
Just found this btw.
https://www.forbes.com/sites/jasone...with-amds-new-vega-powered-apus/#276cca603fbd
Latest 2200g driver (click on W10 64 bit edition)...