can I run gta iv with ATI Radeon HD 5400 series

Solution
Ok, thats better. Still missing exact model of graphics card. The 5400 series can be different cards, I just assume HD 5450. You also didn't specify exact cpu model, so I assume something which fits your description. The Optiplex is the maker of the pc build. First, here the system specs for this game:
> https://support.rockstargames.com/hc/en-us/articles/203428177-Grand-Theft-Auto-V-PC-System-Specs

Minimum specs

8 GB ram is enough for even high recommendation. For minimum is required 4 GB and you have 8 GB. PASS

Required gpu: HD 4870 1GB
You have: HD 5450
Very weak. Even if you would overclock it. It have only 30% power of the minimum required graphics card.
> http://www.hwcompare.com/398/radeon-hd-4870-1gb-vs-radeon-hd-5450/
>...


 
Sorry there is a mistake from me I mean gta V or (5). my cumputer is desktop dell core i3 optiplex 7010 cpu 3.30 ghz with 8 gb ram and my operating system is windows 7 ultimate 64 bit
 
Ok, thats better. Still missing exact model of graphics card. The 5400 series can be different cards, I just assume HD 5450. You also didn't specify exact cpu model, so I assume something which fits your description. The Optiplex is the maker of the pc build. First, here the system specs for this game:
> https://support.rockstargames.com/hc/en-us/articles/203428177-Grand-Theft-Auto-V-PC-System-Specs

Minimum specs

8 GB ram is enough for even high recommendation. For minimum is required 4 GB and you have 8 GB. PASS

Required gpu: HD 4870 1GB
You have: HD 5450
Very weak. Even if you would overclock it. It have only 30% power of the minimum required graphics card.
> http://www.hwcompare.com/398/radeon-hd-4870-1gb-vs-radeon-hd-5450/
> http://ht4u.net/reviews/2010/grafikkarten_performance_vergleich_quartal_3_2010/index17.php
> http://www.techspot.com/review/244-ati-radeon-hd-5450/page5.html

Required cpu: Core2Quad @2.4Ghz
You have: Core i3-3220 @ 3.30GHz
Cpu should be fine.
> http://cpuboss.com/cpus/Intel-Core2-Quad-Q6600-vs-Intel-Core-i3-3220

I think, the only real problem is your graphics card. You should upgrade it. With this configuration, you maybe can play at 720p (1280*720 pixel resolution) with lowest possible settings at 20-25 fps with sometimes going down to 10 fps, which will result in stuttering and slowdowns. Just my prediction. And just if you have luck.
 
Solution