can i use a 4 gb and a 2gb ram on a same ddr3 motherboard?

Solution
You can but you shouldn't if the motherboard supports dual memory architecture, as DCMA only works if the RAM capacities match (ideally they should be bought as a matched pair).

Nothing bad will happen if you use two different RAM capacities, but your losing out on what is a worthwhile performance-enhancing feature.

Buying matched pairs has another good point, there's far less chance of the modules not playing nice with each other.
You can but you shouldn't if the motherboard supports dual memory architecture, as DCMA only works if the RAM capacities match (ideally they should be bought as a matched pair).

Nothing bad will happen if you use two different RAM capacities, but your losing out on what is a worthwhile performance-enhancing feature.

Buying matched pairs has another good point, there's far less chance of the modules not playing nice with each other.
 
Solution

MattBeastblood

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Mar 25, 2013
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That's how my PC was made. It came with a 4 and a 2. I bought an extra 4 and 2 too though, they're exact matches too.

Are there any performance issues with having 4+4 and 2+2? Are you losing anything? I do have each pair on separate channels obviously.