I have the Asus ROG Strix B450-F Gaming that I've had since last November and I am very happy with it. I will say that I have read a few posts that stated that the newer BIOS versions have cold boot and RAM OCing issues. So my advice is to use BIOS 1201 if you do get this MB.
I personally wouldn't OC a 2600x, from what I have read it won't get much if any boost in performance.
I bought my 2600 to OC to hopefully get 2600x performance. And from all the benchmarks I have run I achieved my goal and in some cases I have even exceeded it.