Antimatter is already being made in particle accelerators, and it didn't cost trillions of dollars. Do you have a source for that estimate? Maybe they were estimating to produce some large amount (e.g. a kg of antimatter).
home.cern
So far, CERN has made less than 10 nanograms of antimatter and at that rate (which is ~1 nanogram per year if the accelerators are used to do nothing but produce antimatter) would take 1 billion years to produce 1 gram. Production of antimatter at a reasonable rate using particle accelerators would therefore require covering much of the earth in particle accelerators and the energy infrastructure to power them, hence NASA's estimate of $62.5 trillion per gram
The efficiency of antimatter production in particle accelerators is so low that about 1 billion times more energy is required to make antimatter than is finally contained in its mass. Using E = mc^2, we find that 1 gram of antimatter contains:
0.001 kg x (300,000,000 m/s)2 = 90,000 GJ = 25 million kWh
Taking into account the low production efficiency, it would need 25 million billion kWh to make one single gram