crossfire radeon 7660d integrated wit amd a10-5800k and r9 270x

Solution
No it won't crossfire but the 270x will give very decent medium/high setting performance on its own.
The most you can crossfire with is a r7 260 but the 270x is a far better choice.

Baumy15

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R7-250 and below and also a 7850K @ 4.5 Ghz crossfired with a 250 gives you 270X performance
 

Baumy15

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well a GTX 660 has lower clock speeds lower memory speed and even lower memory bus (192 bit) and from comparisons (me and my friend) my 660 always won sometimes by 5-10 frames other times by 30+ and alone you are adding 2 250's together in a x16 bit bus which theoretically doubles performance, memory speed and frame output.

 
^ it doesn't matter mate - the 250 is low end ,you wont get anything near double the performance ( he'll get r7 250 performance+30-40% max) - the memory throughput on the apu is the max you'll get & anything less than 1866 cas 9 will cripple it.
The 270x is far far superior
 

Baumy15

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even still he can buy a 250 for $80 (aus) and crossfire with the ipgu or buy a 270X have a bottleneck waste the igpu and spend an extra $200 (aus