Depends on your workload, if the program has good Quadro drivers then a low end quadro will beat a 1080Ti. If not the Quadro will look like a joke.
If you’re using Adobe premiere then an Intel chip with an iGPU would be preferable because you can use the iGPU to accelerate tasks and from what I’ve heard it hasn’t been optimised for Ryzen yet.
9900K is the best performing CPU and has 8 more threads than the 2nd placed 9700K. Up to you if you think the extra 200 is worth it for you.