Hello, I have MSI z170 m7 that previously working on 16gigs of ram with 2400mhz, today I bought a new 8x2 gigs which happen to be 2666mhz and not 2400, what are the disadvantages of running those both new rams and if I run them as this slot order 1-3 (new) and 2-4(old) would that be fine with quad channeling? or it wouldn't be quad channeling at all due to the difference in ram brands and speeds?