No. Those coolers are intended to be used with cases that have enough case airflow, by way of usually two intake and two exhaust fans, so that the internal temperature is within a few degrees of the outside ambient temperature or in some cases nearly AT ambient if the exchance is rapid enough.
You will never, ever, get anywhere near that kind of cooling with a downdraft cooler no matter what the model is, unless your duct was coming from your freezer or some other kind of refrigeration was employed. They simply do not have the surface area to exchange enough heat nor do the fans on them have enough CFM and static pressure to facilitate that exchange at a rate that would not be overcome by the TDP of the processor.
If you want to run a higher core CPU like the 9900k, you need a much larger case and a good amount of cooling unless you are willing to drop the clocks and disable the boost features, in which case you could do so, or even use a passive cooler, but it would STILL have to be fairly massive, as seen here:
HardOCP Community Forum for PC Hardware Enthusiasts
www.hardocp.com
That being said, you probably COULD get by with a VERY good, top tiered downdraft cooler, but you're going to pay a premium for one capable enough to not encounter thermal issues AND it's going to be loud, because it's much smaller fan is going to have to run very fast in order to get the job done.
I would never consider using that CPU on a small form factor build unless you go with a case model that supports at least a 240mm AIO cooler, and preferably a 280mm model. For air cooling, you are going to want a tower cooler that is at least as capable as something like the Noctua NH-U14S or bigger. Again, you could run a smaller cooler if noise levels don't bother you, but if you don't want to go insane from the CPU cooler fan I'd highly recommend not using any heatsink fan model that doesn't employ at least one 140mm fan.