Two RX 480 4gb. VRAM doesn't mean very much only in VERY HEAVY video editing and VR. I know you are doing productive work but what applications are you using? You could go with a 1070 if you wanna spend some more money.
PCPartPicker part list:
https://pcpartpicker.com/list/2zMYtJ
Price breakdown by merchant: https://pcpartpicker.com/list/2zMYtJ/by_merchant/
CPU: AMD RYZEN 7 1700 3.0GHz 8-Core Processor ($323.19 @ NCIX US)
CPU Cooler: CRYORIG H7 49.0 CFM CPU Cooler ($34.89 @ OutletPC)
Motherboard: Asus PRIME X370-PRO ATX AM4 Motherboard ($159.99 @ B&H)
Memory: G.Skill Ripjaws V Series 16GB (2 x 8GB) DDR4-2133 Memory ($99.99 @ Newegg)
Storage: Zotac Premium Edition 240GB 2.5" Solid State Drive ($69.67 @ Amazon)
Storage: Seagate Barracuda 2TB 3.5" 7200RPM Internal Hard Drive
Video Card: Gigabyte GeForce GTX 1070 8GB Windforce OC Video Card ($379.00 @ Jet)
Case: Thermaltake Versa H22 Window ATX Mid Tower Case ($42.99 @ SuperBiiz)
Power Supply: SeaSonic S12II 620W 80+ Bronze Certified ATX Power Supply ($49.90 @ B&H)
Wireless Network Adapter: Intel 7260HMWDTX1 PCI-Express x1 802.11a/b/g/n/ac Wi-Fi Adapter ($58.60 @ Amazon)
Total: $1218.22
Prices include shipping, taxes, and discounts when available
Generated by PCPartPicker 2017-04-01 20:00 EDT-0400